OverviewRxNav is a browser for several drug information sources, including RxNorm, RxTerms and NDF-RT. RxNav finds drugs in RxNorm from the names and codes in its constituent vocabularies. RxNav displays links from clinical drugs, both branded and generic, to their active ingredients, drug components and related brand names. RxNav also provides lists of NDC codes and links to package inserts in DailyMed. The RxTerms record for a given drug can be accessed through RxNav, as well as clinical information from NDF-RT, including pharmacologic classes, mechanisms of action, physiologic effects and drug-drug interactions.
Starting RxNavTo start RxNav, click on "Launch RxNav" if the link is present; Otherwise, click on "Download and install the lastest JRE and RxNav". You will arrive at the Sun download homepage, browse to find the JRE download link, and install it. Then return to this RxNav home page, where the link now should read "Launch RxNav" and RxNav installation will be automatically launched. During installation, you can elect to have the shortcut on your desktop.
For Firefox users, open with Java Web Start Launcher.
RxNav code is digitally signed. You need to accept its security certificate to launch the browser.
RxNav uses Java Web Start Technology and requires JRE 1.6 or higher.
Using RxNavSearching Basics
RxNav is capable of searching for drug information using a number of different source identifiers. The table below shows the many identifiers by which a user can search.
Search Types in RxNav
|String||Tylenol||the concept name strings|
|AMP ID||2050||the Alchemy Marketed Product Id (AMP ID) from Gold Standard Alchemy (SAB:GS)|
|ANDA||ANDA007581||the FDA Abbreviated New Drug Application identifier.|
|ATC||M02AA01||the Anatomical Therapeutic Chemical (ATC) identifier (SAB:ATC)|
|GCN_SEQNO||009172||the Generic Code Sequence Number from First Databank Inc (SAB:NDDF)|
|GFC||108077||the Generic Formula Code (GFC) from Micromedex DRUGDEX (SAB:MMX)|
|GPPC||14559||the first five characters of the Generic Product Packaging Code from Master Drug Data Base (SAB:MDDB). Medi-Span, a division of Wolters Kluwer Health|
|HIC_SEQN||004489||the ingredient identifier from First Databank Inc (SAB:NDDF)|
|LISTING_SEQ_NO||203855||the FDA generated unique identification number for each product from FDA National Drug Code Directory (SAB:MTHFDA)|
|MESH||D000212||a Subject Medical Headings (MeSH) identifier from the National Library of Medicine (SAB:MSH).|
|MMSL_CODE||CD1001||a derived identifier that combines the Term type (TTY) and the Multum Mediasource Lexicon (SAB:MMSL) numeric code. First two letters represent the term type: BD, BN, CD, GN or IN.|
|NDA||NDA021400||the FDA New Drug Application identifier|
|NDC||00378802505||the National Drug Code (NDC) from the National Drug Code Directory|
|NUI||N0000148200||the National Drug File Reference Terminology (NDF-RT) Unique Identifier (SAB:NDFRT)|
|RXCUI||202433||the RxNorm concept unique identifier|
|SNOMED ID||1039008||the SNOMED CT concept identifier from the US edition of SNOMED Clinical Terms drug information (SAB:SNOMEDCT_US). SNOMED International|
|SPL_SET_ID||1C5BC1DD-E9EC-44C1-9281-67AD482315D9||the FDA Structured Product Label Set Identifier|
|UMLS CUI||C0000266||the Unified Medical Language System (UMLS) Concept Unique Identifier|
|UNII_CODE||LVX8N1UT73||the FDA Unique Ingredient Identifier Code.|
|VUID Number||4021359||the Veterans Health Administration Unique Identifier from the Veterans Health Administration National Drug File (SAB:VANDF)|
The default identifier is a text string. To change to another search identifier type, simply select an entry from the "Search By:" pull-down menu and enter the identifier in the search box and hit the carriage return or click on the "Search" button.
For a string search, RxNav will display a list of suggested names in a popup window beneath the search string box. The suggested names are ingredients or brand names and will be displayed after at least four characters are entered in the search string box. The user can then select an entry from the list using either the mouse or the up/down arrow keys or can continue typing in the search string box.
When no valid entries are found by RxNav, a popup menu is displayed indicating the term was not found. A list of spelling suggestions will be displayed for a string search in order of closeness to the entered term. The user can select from this list to continue the search.
Filtering based on concept attributes
To the right of the search box, a filter dropdown list allows users to tailor the graph based on three concept attributes - prescribable drug, human drug and veterinary drug.
Selection of more than one filter means that the displayed concepts contain all the filter conditions. Subsequent searches in RxNav will use the filter settings.
If the filter settings result in no concepts to display, a popup window shown below will be displayed.
Changing the Look of the Graph
The look of the RxNorm graph can be changed through the view dropdown menu.
There are four view options:
- Group View. This is the displayed view when users enter RxNav.
- Form View. The Form View is similar to the Group View, except it contains Clinical Dose Form, Branded Dose Form and Dose Form windows instead of Clinical Dose Form Group, Branded Dose Form Group and Dose Form Group.
- Simplified View. The Simplified View contains only the Ingredient, Brand Name, Clinical Drug or Pack and Branded Drug or Pack boxes.
- Table View. The Table View contains the drug concepts in a table form.
Multiple Ingredient Search
The string search allows users to search on multiple ingredients. Starting in September 2010, the RxNorm data set contains multiple ingredient concepts whose names appear in the suggestions list. Alternatively, type the ingredient names separated by plus (+) signs in the search field. For example, "acetaminophen + aspirin". RxNav will display all related concepts which contain at least all of the specified ingredients. Each ingredient will be checked separately for spelling, and alternate suggestions, if any, will be given.
When searching by RXCUI, multiple RXCUIs separated by plus (+) signs can be specified in the search field. For example, entering "161 + 1191" in the search field will display all the related concepts containing acetaminophen (RXCUI=161) and aspirin (RXCUI=1191).
Viewing Long Concept Names
Sometimes concept names are longer than the display area in the term type tables. Double clicking on the table header (the # elements row) will provide a popup display of the term type table which can be resized to view the long names. Closing the popup display will restore the original term type table.
Using the Copy Button
Next to the Status area in the RxNorm Graph view is the Copy button. The Copy button can be used to copy concept information to external sources such as a spreadsheet. The copy button saves the highlighted concepts and prepends the RxCUI and a tab character to each concept name. The copy buffer can then be pasted into another document.