RxClass Overview
The RxClass Browser is a web application for exploring and navigating through the class hierarchies to find the RxNorm drug members associated with each class.

The RxClass API is available for users to include RxClass data in their applications.

RxClass links drug classes with several drug sources to their RxNorm drug members (ingredients, precise ingredients and multiple ingredients).

RxClass allows users to search by class name or identifier to find the RxNorm drug members or, conversely, search by RxNorm drug name or identifier to find the classes that the RxNorm drug is a member of.

Class Types

RxClass contains nine drug class trees:

Sources of Drug-Class Relations

There are five sources which associate generic drugs to the classes listed above.
Note: the last three sources - DailyMed, NDFRT and FDASPL - contain overlapping and redundant associations of drugs to some of the class trees (see tables below), so to avoid confusion only one of those sources is selected at any given time in RxClass.

The following table lists the drug sources and the classes they associate with .

Class \ Source ATC    MeSH   DailyMed FDASPL NDFRT 
ATC1-4    X
MeSHPA     X
EPC       X      X
Chem       X      X      X
Disease      X
MoA       X      X      X
PE       X      X      X
PK      X
VA      X

Relationships to Drug Classes

The following table shows the relationships each drug source uses to identify with the drug class.

Drug Source Relation Drug Class Description
ATC (level 5) ATC1-4 Drug members of an ATC class
MeSH MeshPA Drug members of a MeSH Pharmacologic Action
DailyMed has_EPC EPC Drug members of a FDA Established Pharmacologic Class
DailyMed has_Chemical_Structure Chem Drugs that have a chemical structure
DailyMed has_MoA MoA Drugs that have a Mechanism of Action
DailyMed has_PE PE Drugs that have a Physiologic Effect
FDASPL has_EPC EPC Drug members of a FDA Established Pharmacologic Class
FDASPL has_Chemical_Structure Chem Drugs that have a chemical structure
FDASPL has_MoA MoA Drugs that have a Mechanism of Action
FDASPL has_PE PE Drugs that have a Physiologic Effect
NDFRT CI_ChemClass Chem Drugs that are contraindicated with a chemical class
NDFRT has_ingredient Chem Drugs that are members of a chemical class
NDFRT has_active_metabolites Chem Drugs that have active metabolites in a chemical class
NDFRT CI_with Disease Drugs that are contraindicated with a disease
NDFRT induces Disease Drugs that induce a disease
NDFRT may_diagnose Disease Drugs that may diagnose a disease
NDFRT may_prevent Disease Drugs that may prevent a disease
NDFRT may_treat Disease Drugs that may treat a disease
NDFRT CI_MoA MoA Drugs that are contraindicated with a Mechanism of Action
NDFRT has_MoA MoA Drugs that have a Mechanism of Action
NDFRT CI_PE PE Drugs that are contraindicated with a Physologic Effect
NDFRT has_PE PE Drugs that have a Physiologic Effect
NDFRT has_PK PK Drugs that are members of a Pharmacokinetics Class
NDFRT site_of_metabolism PK Drugs that have a site of metabolism in a Pharmacokinetics Class
NDFRT has_VAClass VA Clinical drugs that are members of a VA Class

 
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